Symbol
Name
ID

Bcl2l1
BCL2-like 1
MGI:88139

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Abnormality of blood and blood-forming tissues

Leukocytosis

Abnormal granulocyte morphology

Abnormal basophil morphology

Acute lymphoblastic leukemia

Ph-positive acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemias

Chronic myelogenous leukemia

Myeloproliferative disorder

Thrombocytopenia

Thrombocytosis

Lymphoma

Splenomegaly

Hepatosplenomegaly

Disease(s) Associated with BCL2L1

acute lymphoblastic leukemia

chronic myeloid leukemia

pancreatic cancer

Mouse Phenotypes

decreased T cell proliferation

increased T cell proliferation

decreased thymocyte number

decreased double-positive T cell number

extramedullary hematopoiesis

increased megakaryocyte cell number

thrombocytopenia

decreased memory T cell number

increased memory T cell number

decreased IgG1 level

abnormal T cell physiology

abnormal memory T cell physiology

abnormal platelet physiology

Availability

Mouse Genotype

Bcl2l1^Plt20/Bcl2l1^Plt20

Bcl2l1^tm1Cant/Bcl2l1^tm1Cant

Bcl2l1^Plt16/Bcl2l1⁺

Bcl2l1^Plt20/Bcl2l1⁺

Bcl2l1^Plt20/Bcl2l1^Plt16

Bcl2l1^tm1Dlo/Bcl2l1⁺

Bcl2l1^tm1Dlo/Bcl2l1^Plt20

Tg(Lck-Bcl2l1)1Cant/?

Bcl2l1^tm1Ywh/Bcl2l1^tm1Ywh
Tg(Lck-cre)548Jxm/? (conditional)

Bcl2l1^tm1Dlo/Bcl2l1^tm1.1Mam
Tg(Aicda-cre)9Mbu/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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